This means that in this class of obese people, if we operate on a thousand, two will die. If you take these same thousand people and just let them carry on the same way (with medical treatment, etc.) HALF of them would be dead in 20 years! In fact, the five year mortality of these patients is high enough to justify bariatric surgery.

Even though this is pretty impressive stuff to demonstrate how life-saving and life-altering bariatric surgery can be, what happens to an individual case where the patient dies? For that family, the mortality rate is 100%! Can things be any worse for them? No.

Therefore, if we could try and reduce the mortality of surgery even further, why would we not do it?

If we could weed out the highest risk cases, it would be half the battle won. We could then simply try not to operate on this high-risk class of patients, UNLESS there is a clear and explicit understanding and acceptance that they have a significant chance of dying within a month of surgery.

So the highest risk is seen in these groups:

1. Elderly
2. Males
3. High BMI
4. Smokers, alcoholics
5. History of pulmonary embolism/DVT
6. Re-do bariatric surgery

• Causes of 30-day bariatric surgery mortality: with emphasis on bypass obstruction– Mason EE, Renquist KE, Huang YH, Jamal M, Samuel I.
• The SOS Study: Sjöström
• The Pennsylvania bariatric mortality study
• Long-Term Mortality after Gastric Bypass Surgery: Ted D. Adams, et al.
• Medicolegal analysis of 100 malpractice claims against bariatric surgeons: Cottam D, Lord J, Dallal RM, Wolfe B, Higa K, McCauley K, Schauer P.

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It has always been a given for generations that ‘once a diabetic, always a diabetic’. Absolutely like the truism for high blood pressure, asthma and hypothyroidism. You know that if you are unlucky enough to get these labels stuck on you, you are going to take pills or injections all your life and suffer the disease as it progresses into making each organ weaker than ever before. No more.

Riya, a plump 50-year-old diabetic who was taking insulin injections for many years, was fed up of her lifestyle and the fact that she was developing complications of diabetes and high blood pressure. Being highly educated, she searched the Internet for newer options. Every website she visited mentioned high cure rates after gastric bypass surgery. She came to us at Belle Vue Clinic, where we did the same surgery on her (keyhole method). Riya’s blood sugar, always in the high 300s, normalized immediately after her surgery. Discharged after a couple of days, she joined back her school in a week, no longer worried about her blood sugar. Her colleagues are now asking her about her secret – how did her weight and blood sugar get under control so quickly?

In 1994, an American doctor called Walter Pories published a scientific paper provocatively titled, “Who would have thought it? An operation is the cure for Type II Diabetes Mellitus!” This paper showed the astonishing results that an operation called gastric bypass led to patients getting cured of diabetes in nearly 90 percent of cases. Blood sugar levels stay normal even several years after the operation.

Since then, this kind of operation, called ‘Metabolic Surgery’ or ‘Bariatric Surgery’ has become a standard across the globe.

What is done in the gastric Bypass?

We staple the stomach to form a very small pouch. When swallowed food comes from the food-pipe   into this pouch, it meets a dead end. So we need to create a way for the food to go down. To do this, we take the small intestine up and create a channel between it and the stomach pouch. So, now the food goes into the small gut, bypassing most of the stomach and upper small bowel.

How Does This Work?

This works by reducing the stomach’s capacity to take in food, leading to satiety upon consuming a small portion of around an ounce of fluid. There is reduced spike in blood glucose after food (less volume + less absorption= low nutrient absorption).

The net effect of this operation is that undigested food reaches the small bowel, leading to the release of some hormones called incretins. These incretins (a group of around 200 chemicals) act to bring down the blood sugar levels and also halt the deterioration of pancreatic hormonal function that is the hallmark of Type II Diabetes Mellitus.

It is now clear that the alarming rise in cases of diabetes is linked to the widespread obesity in towns and cities. Indeed, 80 percent of new diabetics are fat to varying degrees. So far, doctors have been advising diabetics to lose weight by diet control and exercise, and to take medicines for diabetes. To a large extent, this is a hit-and-miss method of treatment, as there is no sure and predictable response in patients, largely because everyone differs in how strictly they follow their dietary discipline. Most people cheat on their diet, don’t exercise beyond the irregular morning walks and keep getting new complications of diabetes every year.

Most of these patients who undergo the gastric bypass procedure are also very obese. Says Dr. Arindam Ghosh, a bariatric surgeon based in Ludhiana’s Apollo Hospital, “Many of my diabetic patients are obese Punjabis weighing up to 200 kgs. Some of them live in the US and Canada, where the obesity levels are far greater than in India.”

Even though increasing numbers of our patients are searching the Internet daily for information, awareness levels are still abysmal. Patients think surgery involves physical removal of fat from their body. The younger generation is taking the lead. Yogesh Sharma, a 19 year old student who weighed 168 kgs, came to me for surgery to reduce his weight and cure his diabetes after convincing his parents that his decision was the correct one. To their credit, the Sharmas saw merit in the scientific approach. Most people are, however, very scared of the very word ‘surgery’ and would rather see their lives slowly but surely getting spoiled by disease.

Many people like Ruchita Doshi, a 57-year-old lady who has undergone spine surgery, regret their decision, “I wish I had undergone bariatric surgery before. My obesity led to arthritis and spine disease for which I needed to spend rupees three lakhs on treatment. Now they say I cannot be operated as I am undergoing dialysis because of diabetic nephropathy (end stage kidney disease).” Ruchita shares the opinion of many doctors that surgery for diabetes cure would have offset the costs of the complications of the primary disease. What are you doing about your obesity and diabetes?

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One such area of concern has been the depression and even suicidal tendencies seen in some cases after bariatric surgery. There are various case reports of depression and suicides after bariatric surgery in the literature ^1-4.

Recently a paper published in a reputed journal made an attempt to analyse this rather alarming problem ⁵. After critically analyzing these papers it was suggested that some papers suffered from methodologic problems such as small sample size, failure to use validated assessments of psychopathology and absence of appropriate comparison groups (for example , how many candidates were already depressed and having suicidal ideation before bariatric surgery).

One  study found out that many of the patients undergoing bariatric surgery already have psychiatric disorders in the form of anxiety , mood , and personality disorder ⁶. In another study the extremely obese subjects were found to experience increased suicidal ideation than their normal ­­­­weight counterparts ⁷. This may be partly responsible for the increased negative psychosocial effects seen in patients after bariatric surgery.

On the other hand, there are many papers  that suggest that Bariatric surgery is  associated with significant improvements in psychosocial status. Most psychosocial characteristics, including symptoms of depression and anxiety, health-related quality of life, self-esteem, a­­nd body image, improve dramatically in the first postoperative year.^8-13

Unfortunately, a minority of patients appears to struggle with numerous psychological issues postoperatively. Although the evidence submitted in the literature to prove the adverse psychosocial outcome arising as a direct result of bariatric surgery is far from convincing due to the reasons stated above, it is probably a good policy to involve a mental health professional in all cases before performing such surgery. ­­

References:

1.    Higa KD, Boone KB, Ho T. Complications of the laparoscopic Roux-en-Y gastric bypass: 1,040 patients–what have we learned? Obes Surg. 2000;10(6):509-513.

2.    Hsu LK, Benotti PN, Dwyer J, et al. Nonsurgical factors that influence the outcome of bariatric surgery: a review. Psychosom Med. 1998;60(3):338-346.

3.    Waters GS, Pories WJ, Swanson MS, Meelheim HD, Flickinger EG, May HJ. Long-term studies of mental health after the Greenville gastric bypass operation for morbid obesity. Am J Surg. 1991;161(1):154-157.

4.    Adams TD, Gress RE, Smith SC, et al. Long-term mortality after gastric bypass surgery. N Engl J Med. 2007;357(8):753-761.

5. David B. Sarwer,  Anthony N. Fabricatore, P et al. Primary Psychiatry. 2008;15(8):50-55

6.    Kalarchian MA, Marcus MD, Levine MD, et al. Psychiatric disorders among bariatric surgery candidates: relationship to obesity and functional health status. Am J Psychiatry. 2007;164(2)328-334.

7.    Dong C, Li WD, Li D, Price RA. Extreme obesity is associated with attempted suicides: results from a family study. Int J Obes (Lond). 2006;30(2):388-390.

8.    Bocchieri LE, Meana M, Fisher BL. A review of psychosocial outcomes of surgery for morbid obesity. J Psychosom Res. 2002;52(3):155-165.

9.    Herpertz S, Kielmann R, Wolf AM, Langkafel M, Senf W, Hebebrand J. Does obesity surgery improve psychosocial functioning? A systematic review. Int J Obes Relat Metab Disord. 2003;27(11):1300-1314.

10.    van Hout GC, van Oudheusden I, van Heck GL. Psychological profile of the morbidly obese. Obes Surg. 2004;14(5):579-588.

11.    Sarwer DB, Wadden TA, Fabricatore AN. Psychosocial and behavioral aspects of bariatric surgery. Obes Res. 2005;13(4):639-648.

12.    Herpertz S, Kielmann R, Wolfe AM, Hebebrand J, Senf W. Do psychosocial variables predict weight loss or mental health after obesity surgery? A systematic review. Obes Res. 2004;12(10):1554-1569.

13.    van Hout GC, Boekestein P, Fortuin FA, Pelle AJ, van Heck GL. Psychosocial functioning following bariatric surgery. Obes Surg. 2006;16(6):787-794.

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(B, a young patient who was 165 kgs, before surgery)

The same applies to ‘morbid obesity’. We call this ‘Clinically Severe Obesity’ now. Allegedly because the term ‘morbid’ is negatively prejudiced against the obese. Some time soon, they will replace the term ‘obese’ and call it ‘adiposely challenged’ or something, I have no doubt!

All said and done, what does it change? Does it change the fact that obesity kills more people than most other diseases today? If you want to know why obesity is not considered being healthy, have a look at this list of diseases associated with it. The term we use is ‘co-morbidity’.

(from Gen Surg News)

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If you have had bariatric surgery and are now having reflux, what now?

(Are you worried about your reflux? Pic source: here)

We need to see what procedure you had. If you had a Band, tough luck! Because, as we mentioned before, the Band does cause reflux and also esophageal dilatation. Now, many surgeons will quickly accuse me of bias here. To which I plead guilty. I have always maintained that the Band is not exactly my favorite operation. While I maintain that it causes reflux in a lot of patients, there are conflicting reports worldwide.

For example, in Dixon’s study, they have found fantastic results after the Lap Band in terms of reflux symptoms and otherwise, too. Ten years later, the Australians reported excellent results in this paper.

(your favorite antacid may help. Pic: here)

After sleeve gastrectomy, reflux is temporary but may be distressing. If you have this problem, here is a list of what to do:

* Chew your food slowly or drink your liquids slowly.

*Avoid processed carbs

*Stay away from coffee, alcohol and tea

*Stop smoking, really stop it, will you?!

* Walk around after dinner

* Take an hour or two (or more) to sleep after dinner

* Keep the head end of the bed elevated

* Take PPIs as prescribed. PPIs are drugs that banish acid secretion.

* For short term burning sensation, drink  little cold water and have some preparation like Mucaine gel or Xylocaine viscous (local anesthetic).

* Contact the bariatric team for further advice.

After sleeve, reflux may be distressing and persistent in a small subset of patients. As this recent paper says, there may be an association between a wider proximal stomach tube and a narrower distal tube. This means that the upper part of the stomach tube is wider than the lower part. However, this is not related to the size of the bougie (the rod like thingie that is used as a sizer for the tube prior to stapling). Whether 3 cm or 6 cm of the lower part of the stomach (the antrum) is left behind has no relationship to the severity of reflux. Most of these patients also respond well to medical treatment.

Well, that should wrap up the subject pretty much for you! Please get in touch with us if you need more information.

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So let us now assume that you are awaiting bariatric surgery and have reflux symptoms. So how does your reflux have an implication on your surgery? Will bariatric surgery (after all, we are operating on the stomach) make your reflux worse or better?

Let us take this procedure by procedure:

The Band: The band produces a mechanical obstruction right below the junction of the food pipe and the stomach. While this produces a barrier for the downward descent of food and accounts for the restriction in food intake after its placement, it does just the reverse for acid reflux. In other words, it tends to make reflux symptoms worse. Not to waste too many words on this, the Band is out if you have reflux.

The Gastric Bypass: This is the ultimate anti-reflux operation. It has a nearly 100 percent success in banishing reflux. After all, the pouch is separated from the stomach, where most of the acid is produced. What more, the small gut (jejunum) that is connected to the pouch acts to drain the acid away from the food pipe downwards. The special “Roux-en-Y” way in which we attach the jejunum to the pouch is the key to banishing reflux disease.

Sleeve Gastrectomy: Sleeve gastrectomy converts the stomach into a straight tube. In addition, it removes the part of the stomach from where muscle fibers go as a sling to loop around the LES (Lower Esophageal Sphincter). So it is possible that this operation weakens the sphincter and enhances reflux. In fact, clinically, most patients tend to have some degree of reflux after the sleeve, but this is self-limited and resolves soon. Once weight loss is begins, reflux also tends to reduce and go away.

In patients with a lax esophageal hiatus (the gap in the diaphragm through which the food pipe enters the abdomen) or with hiatus hernia, the sleeve can be done along with a repair of the hiatus (a procedure known as cruroplasty). This is also an accepted modality of treating reflux in the bariatric patient.

So the sleeve is a good bariatric procedure with a fairly good tolerance for the patient with some degree of pre-existing reflux symptoms.

The Duodenal Switch: This operation does not do much more than the sleeve for reflux. Indeed, the sleeve gastrectomy is the first part of the DS operation.

To sum up, if you are looking at bariatric surgery and you have symptoms and evidence of reflux esophagitis, then you should NOT consider the Band. If reflux is making your life miserable, then a bypass will be the best operation for you. If you don’t want the bypass for any reason, by all means consider the sleeve procedure.

In Part Three, we will examine the rest of the reflux story.

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While a detailed discussion on the why’s and how’s of acid reflux are outside our syllabus in today’s class, it is important to just get an idea of the basic reasons why gastric acid gets up (against the tide) into the food pipe (esophagus).

The normal junction between the esophagus and the stomach is marked by a whorl of muscle fibers of the two organs that functionally works as a valve. This valve, called the LES (Lower Esophageal Sphincter) allows food to pass from the food pipe into the stomach, but not the other way. If it weren’t for this, we would keep burping up food into the mouth like infants. Now that wouldn’t impress our girl friends, would it?

(diagrammatic representation of the area of our interest. Pic source: www.chw.org)

In certain circumstances, the function of the LES is impaired, and the net result in the reverse entry of gastric acid into the food pipe (a place that is not adapted to acid pH). This happens if you eat too much, or oily/spicy/processed food, drink too much coffee or alcohol, or if you smoke. I am not even scratching the surface here.

In cases where the pressure within the abdomen is very high (as in advanced pregnancy or severe obesity) the excess pressure on the stomach overcomes the resistance of the lower esophageal sphincter and causes reflux. The food pipe gets inflamed as a result of the acid attack (reflux esophagitis).

In many instances there is a condition called hiatus hernia that causes severe reflux. This condition occurs when the junction between the food pipe and the stomach slides up into the chest cavity, as a result of which the positive intra-abdominal pressure pushes up the acid from the stomach into the esophagus, which is located in a negative (low) pressure zone inside the chest cavity.

With this background, we need to understand that most obese patients, specially those being considered for bariatric surgery, are chronic sufferers of reflux. However, it is important to understand that many upper abdominal or digestive symptoms (like pain after eating, vomiting, “gas”, for example) are due to associated gallstone disease.

Obviously, each of this is deserving of treatment on its own merit.

When we see patients, we evaluate the patient’s symptoms and consider reflux as a clinical diagnosis. The diagnosis is documented by other studies like upper GI endoscopy, barium study and esophageal manometry.

An ultrasound is always done to exclude gallstone diseases and to see the state of the liver. Fatty liver is almost always a given in the bariatric patient before surgery.

Now that we know what reflux is, how it occurs in the obese patient and how we detect it, we need to know what to do about it.

That will be Part Two.

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